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Percutaneous Cryoablation — Soft Tissue

Interventional Radiology · Cochin Hospital AP-HP · Paris

❄️ Oncology · Interventional

Percutaneous Cryoablation — Soft Tissue Tumours

CT/ultrasound-guided · −40°C · No surgery · Local or general anaesthesia · Day case · Paris Cochin AP-HP

📖 What is percutaneous cryoablation?

Cryoablation uses extreme cold (temperatures of −40°C) to destroy tissue. One or more cryoprobes are inserted percutaneously (through the skin) into the target lesion under CT or ultrasound guidance. Freeze–thaw cycles create an "ice ball" that ablates the lesion while sparing surrounding structures.

Key advantage over radiofrequency ablation: the ice ball is clearly visible on CT and ultrasound, enabling precise real-time control of the ablation zone. Cryoablation is preferred near sensitive structures (nerves, bile ducts, ureter) where thermal ablation would carry higher risk.

🎯 Indications

🌸 Abdominal wall endometriosis

World-leading expertise at Cochin AP-HP since 2014 (Pr Dohan). Cryoablation of parietal endometriosis nodules (C-section scar endometriosis). 80–95% efficacy. General anaesthesia.

🦶 Morton's neuroma

CT/ultrasound-guided cryoablation of the intermetatarsal neuroma. Immediate weight-bearing. No scar. Local anaesthesia. 70–85% pain reduction.

🩻 Renal tumours

T1a renal cell carcinoma — cryoablation as alternative to surgery. Preferred near renal collecting system or ureter.

🦴 Bone & soft tissue

Osteoid osteoma (small bone tumours), desmoid tumours, soft tissue masses.

FAQs

Both destroy tissue but by different mechanisms — cold vs heat. Cryoablation is preferred near sensitive structures (nerve, ureter, bile duct) because the ice ball provides a sharp margin and is clearly visible on imaging. RFA is faster and preferred for larger lesions away from critical structures.
Performed under local anaesthesia (small lesions) or general anaesthesia (abdominal procedures). Post-procedure discomfort is typically mild and managed with oral analgesia for 2–5 days.
Usually a single session is sufficient. If the ablation is incomplete or the lesion recurs, a second session can be performed.

🔗 Related pages

→ Endometriosis cryoablation→ Morton's neuroma→ Kidney tumour ablation→ 🇫🇷 Version française