🏥 TACE Centre — Hepatic Chemoembolization — Cochin AP-HP Paris

Quick answer

The hepatic chemoembolization centre at Cochin AP-HP is an expert centre in interventional liver oncology. TACE is the reference treatment for intermediate-stage hepatocellular carcinoma, combining local chemotherapy and arterial occlusion.

📖 Chemoembolization (TACE) Centre at Cochin AP-HP

The Hepatic Chemoembolization Centre at Cochin AP-HP is an expert centre in interventional liver oncology. TACE (Trans-Arterial ChemoEmbolization) is the reference treatment for intermediate-stage hepatocellular carcinoma (HCC) (BCLC B) and is also used for the palliative treatment of certain liver metastases. We have intra-procedural high-resolution CT guidance — a unique high-resolution scanner enabling high-resolution intra-procedural imaging and optimized dosimetry.

All cases are discussed at a hepatic oncology tumour board bringing together hepatologists, liver surgeons, oncologists and interventional radiologists. We perform conventional TACE (Lipiodol + chemotherapy) and DEB-TACE (Drug-Eluting Beads) with prolonged chemotherapy release. 100% covered at Cochin AP-HP.

🎯 Indications

• BCLC stage B HCC (intermediate): multiple tumours without portal vein thrombosis or extrahepatic metastases
• HCC as a bridge to liver transplantation (UNOS downstaging)
• HCC as a bridge to transplantation while on the waiting list
• Unresectable liver metastases (colorectal, neuroendocrine, uveal)
• HCC in combination with immunotherapy (research protocols)
• Symptomatic secondary liver tumours (carcinoid, GIST)

🔧 Our techniques

📊 Results

🔄 TACE in combination

TACE can be combined with:

• Radiofrequency or microwave ablation (TACE-RFA) for lesions ≤ 5 cm
• Immunotherapy (atezolizumab + bevacizumab) — active research protocols at Cochin
• Y90 radioembolization for extensive disease or in cases of segmental portal vein thrombosis

→ Learn more about Y90 radioembolization  |  🇫🇷 → Liver expert centre

❓ Frequently asked questions

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