🇫🇷 FR 🇬🇧 EN
Cochin University Hospital – AP-HP · Paris Cité University
← Interventional Radiology 🇮🇹 IT
Cochin University Hospital – AP-HP · Paris Cité University
Interventional Radiology Hôpital Cochin ri.cch@aphp.fr
Interventional Radiology
Hôpital Cochin Port-Royal AP-HP AP-HP
Interventional Radiology

Hôpital Cochin · AP-HP · Paris Cité University

Tumour ablation

Percutaneous liver tumour ablation

By microwave, radiofrequency or irreversible electroporation

What is percutaneous tumour ablation?

Liver tumours are destroyed by heat (radiofrequency ablation, microwave) or, for lesions close to the bile ducts or pancreatic duct, by electrical pulses (irreversible electroporation — IRE/NanoKnife), via percutaneous image-guided access without surgery.

Why choose this technique?

  • It provides targeted local treatment of primary or secondary liver lesions
  • It preserves as much healthy liver as possible
  • An alternative to surgery with similar efficacy, fewer complications and a shorter hospital stay for tumours smaller than 3 cm
  • It is also possible for larger lesions while awaiting surgery or liver transplantation

Who is this method for?

All indications are determined at a dedicated multidisciplinary team meeting (hepatology, digestive oncology, etc.).

  • Single or multiple liver tumours smaller than 3 cm (sometimes possible for larger lesions)
  • Hepatocellular carcinoma and liver metastases

How does it work?

1

Short hospital stay (usually 1 to 3 days)

2

Under general anaesthesia

3

Percutaneous image-guided puncture (ultrasound, CT scan, cone-beam CT ± fusion of several modalities)

4

Protective measures are put in place if needed (carbodissection or hydrodissection)

5

Destruction of the tumour using the method determined by its location and the patient's history

6

Short post-procedure monitoring

What is the recovery like?

  • Moderate pain over the abdominal wall is possible
  • Possible but rare complications: haematoma, numbness of the skin near the treated area, exceptional bowel perforation
  • Short hospital stay
  • Radiological follow-up at 1 and 3 months, then every 3 months by imaging

What to prepare before the consultation

If you are referred by a doctor in our centre, we usually have all the necessary information.

  • A recent CT or MRI scan
  • Liver work-up
  • A summary letter from your doctor

🏥 Rapid diagnosis of liver tumours: a dedicated pathway

Cochin Hospital has a rapid diagnostic pathway for liver tumours, in collaboration with the Hepatology Department of Professor Romain Coriat. If you have a liver abnormality detected on imaging, rapid, coordinated management is possible, including a complete diagnostic work-up, discussion at a hepatology MDT meeting and referral to the most appropriate treatment (surgery, interventional radiology, chemotherapy).

Hepatology Department — Cochin Hospital → Tel: 01 58 41 42 43

🚨 PANCREAS FAST TRACK: rapid diagnosis

Cochin Hospital offers multidisciplinary expertise for the rapid diagnosis of pancreatic lesions. If you have clinical, radiological or biological signs suggesting a pancreatic lesion, you can be referred directly to our specialists:

🔪 Hepatobiliary and pancreatic surgery

For surgical resection of tumours of the liver, pancreas and bile ducts. Multidisciplinary care with our interventional team.

chir-digestive-cochin.com →

🔬 Gastroenterology & digestive oncology

Pancreatic cancer, neuroendocrine tumours: RENATEN reference centre. Liver tumours (HCC), colorectal cancer, IBD.

Pancreatic cancer → TNE : RENATEN →

Patient information sheet

📄

Patient information sheet

Download before your consultation or procedure.

📥 Download (PDF)

At a glance — key figures

Liver radiofrequency ablation destroys a liver tumour using heat (90–110 °C) delivered through a needle electrode placed through the skin under ultrasound or CT guidance, with no incision. It is an alternative to surgery for small liver cancers and preserves the healthy liver.

CriterionData
Cancer controlLocal recurrence < 5% at 5 years for tumours < 3 cm — comparable to surgical resection
Treatable tumour sizeIdeally < 3 cm, feasible up to 5 cm (microwave preferred for larger lesions)
IndicationsHepatocellular carcinoma (HCC) on cirrhosis, liver metastases (notably colorectal), bridge to transplantation
ComplicationsUncommon (around 2.4%) vs 22–39% after surgery
LiverPreserved — only the tumour is destroyed, healthy liver is spared
Hospital stayShort (1–2 nights), return to activity within days
CostCovered by French national health insurance at Cochin AP-HP — no out-of-pocket fees

Sources: EASL and BCLC recommendations for hepatocellular carcinoma; large multicentre series. Data validated by the team of Prof. Anthony Dohan, Department of Interventional Radiology, Cochin Hospital AP-HP, Université Paris Cité.

Cost: covered by French National Health Insurance. No additional fees in our centre.

Frequently asked questions

Yes. For small liver tumours (hepatocellular carcinoma or metastases under 3 cm, feasible up to 5 cm), radiofrequency ablation is a recognised alternative to surgery, performed through the skin without incision, preserving the healthy liver.
For small hepatocellular carcinomas (under 3 cm), local recurrence is below 5% at 5 years, comparable to surgical resection, with far fewer complications (around 2.4% vs 22–39%).
Hepatocellular carcinoma (often on cirrhosis) and liver metastases, particularly from colorectal cancer. Ablation may also serve as a bridge treatment while awaiting liver transplantation.
Radiofrequency and microwave destroy the tumour with heat; microwave is faster and more effective for lesions over 3 cm. Cryoablation is preferred near the bile ducts or sensitive structures. All three are available at Cochin AP-HP and the choice is made at the multidisciplinary meeting.
Contrast-enhanced imaging (CT or MRI) at 1 month, then every 3–4 months for the first two years, to confirm complete ablation and detect new lesions early.

Why this page is trustworthy

Written by the Interventional Radiology team at Cochin Hospital AP-HP, Université Paris Cité. Medically reviewed by an interventional radiologist of the department. Last updated: August 2026.

🏥 Le service 📰 Actualités 🔬 Recherche & essais cliniques