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Cochin University Hospital – AP-HP · Paris Cité University
← Interventional Radiology
Cochin University Hospital – AP-HP · Paris Cité University
Interventional Radiology Hôpital Cochin ri.cch@aphp.fr
Interventional Radiology
Hôpital Cochin Port-Royal AP-HP AP-HP
Interventional Radiology

Hôpital Cochin · AP-HP · Paris Cité University

Thyroid radiofrequency ablation

Radiofrequency ablation of benign thyroid nodules

An alternative to surgery for symptomatic thyroid nodules

What is thyroid nodule radiofrequency ablation?

This technique partially or completely destroys a benign thyroid nodule using the heat produced by a radiofrequency needle, inserted percutaneously under ultrasound guidance, without surgery. The radiofrequency current heats the nodule tissue to approximately 60–80°C, destroying the targeted cells while preserving the surrounding healthy thyroid tissue.

Ultrasound guidance for thyroid radiofrequency ablation — Interventional Radiology Cochin
Real-time ultrasound guidance during a thyroid radiofrequency procedure — Interventional Radiology Department, Cochin Hospital.

Why choose this technique?

  • Targeted local treatment of benign thyroid nodules causing symptoms
  • Progressive reduction in nodule volume (on average 50 to 80% at 6–12 months)
  • Preserves healthy thyroid tissue and thyroid function
  • No neck scar, no general anaesthesia
  • No thyroid hormone replacement therapy required
  • No risk of hypoparathyroidism
  • Day-case treatment with rapid recovery (2 days off work)

Who is this method for?

Indications are determined after specialist assessment, in a multidisciplinary team meeting (endocrinology, interventional radiology, surgery).

  • One or more benign thyroid nodules confirmed by biopsy (at least one, often two)
  • Compressive symptoms: difficulty swallowing, sensation of a mass, breathing discomfort
  • Cosmetic concern
  • Solid or predominantly solid nodules, usually ≥ 2–3 cm
  • Patients who do not wish to, or cannot, undergo surgery

How does it work?

1

Admission as a day case: arrival in the morning (usually 7:45 am), return home in the afternoon. You must fast from midnight.

2

Pain-relief ± anti-anxiety premedication on the morning of the procedure

3

Local anaesthesia in the neck: you remain conscious throughout the procedure

4

The radiofrequency electrode is inserted into the nodule under real-time ultrasound guidance

5

Progressive destruction of the nodule using the "moving shot" technique: the interventional radiologist regularly repositions the needle to treat the entire nodule

6

Protective measures if needed (hydrodissection) to move sensitive structures away: recurrent laryngeal nerves, trachea, oesophagus

7

Total session time: 1.5 to 2 hours, including 30 to 60 minutes of the procedure depending on nodule volume

8

A few hours of monitoring, then return home accompanied

💡 During the procedure: it is best to avoid speaking so the thyroid does not move. If you feel any pain, tell the doctor immediately and they will adjust the procedure. The procedure is not painful but may be uncomfortable at times.

What is the recovery like?

Expected, temporary effects:

  • Moderate neck pain, managed with paracetamol for a few days
  • Local swelling or a sensation of neck tightness in the following days
  • Bruising or redness over the treated area (temporary)
  • Slight, temporary increase in nodule volume in the first few days
  • No visible scar
  • Time off work: 2 days

Possible complications:

  • Temporary voice change (recurrent nerve palsy): 1–2%, usually reversible
  • Nodule rupture into the surrounding tissues (2 to 10 weeks afterwards): 2.5%, managed medically
  • Temporary drooping eyelid (ptosis): 0.2%, very rarely permanent
  • Skin or tracheal burn: exceptional

Follow-up after treatment

Over a few months, the nodule gradually decreases in size. The doctor will contact you by phone in the days following the procedure.

  • Follow-up consultation with ultrasound at 6 and 12 months, then annually
  • A second session may be offered at 1 year if volume reduction is insufficient
  • Surgery always remains possible if needed

Our explainer videos

Professor Anthony Dohan introduces the technique and answers frequently asked questions:

Introduction to thyroid radiofrequency ablation

Frequently asked patient questions

Results and follow-up after treatment

What the procedure day looks like

Understanding thyroid nodules

Thyroid nodules are very common: they are found in 50 to 70% of adults on ultrasound. The vast majority are benign and require monitoring only. Only symptomatic benign nodules (difficulty swallowing, a sensation of neck tightness, a visible goitre) or hypersecreting nodules (hyperthyroidism) require treatment.

What is thyroid radiofrequency ablation?

Radiofrequency (RF) is a thermal ablation technique that uses electromagnetic waves to heat and destroy the nodule tissue from within, under real-time ultrasound guidance. A fine electrode is inserted into the nodule to be treated. No scar, no general anaesthesia.

Expected outcomes

  • Nodule volume reduction of 50 to 80% within 6 to 12 months
  • Disappearance or marked improvement of compressive symptoms
  • Correction of hyperthyroidism in autonomously functioning nodules
  • Thyroid function is preserved: no induced hypothyroidism
  • Durable results at 3 years documented in the international literature

What to bring to your consultation

  • A recent thyroid ultrasound with nodule measurements
  • Fine-needle aspiration (FNAC) with a Bethesda II or III result confirming benignity
  • Thyroid work-up (TSH, free T4)
  • For a hot nodule: thyroid scintigraphy

What to prepare before the consultation

  • Results of your thyroid fine-needle aspiration(s)
  • Your most recent thyroid ultrasound
  • A recent thyroid work-up (TSH, T4)
  • A referral letter from your endocrinologist or GP

📄 Full information leaflet: a detailed information leaflet will be given to you during the consultation, in line with the recommendations of the French National Authority for Health (HAS). It covers all the benefits, risks and alternatives of the treatment.

🏠 Home recovery support — Midiperf Santé

We work in partnership with Midiperf Santé, a home-care provider, for a smooth recovery at home after your procedure. A dedicated nurse contacts you before discharge, visits your home on day 1 with all necessary equipment, and follows up within 48 hours. 24/7 on-call service if needed.

midiperf-sante-34.fr →

Patient information sheet

📄

Patient information sheet

Download our patient information sheet before your appointment.

📥 Download (PDF)

Cost: covered by French National Health Insurance. No additional fees in our centre.

Direct contact

For any question before or after the procedure: